Tecan evo

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Tecan Freedom EVO Gen-Probe 100/4 DTS. used. Manufacturer: Tecan; Model: Freedom EVO; The Tecan Freedom EVO GEN-Probe 100 /4 DTS is a liquid handling instrument designed for

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June 9, 2015 | Customer News June 9, 2015 Tecan’s Freedom EVO® ideal for automated high throughput cell separation Männedorf, Switzerland, June 9, 2015 – The Karlsruhe Institute of Technology has automated high throughput cell separation protocols using aqueous two-phase systems (ATPS) on a Freedom EVO® 200 liquid handling platform. PhD student Sarah Zimmermann explained: “ATPS offers many advantages compared to antibody-based methods of cell separation; cost-effectiveness, scalability and very mild, gentle conditions for purification of cell products. Initially, we performed ATPS manually, but this is tricky and can give rise to large errors and unreproducible data. Automation was the way forward.” “The Freedom EVO workstation has enabled us to establish automated high throughput screening, allowing rapid, directed design of purification protocols for therapeutic cells. The process is more rapid and reproducible than manual methods, enabling 96 samples to be processed in four hours. Volumes between 10 and 990 µl are pipetted using the Liquid Handling Arm with fixed tips, with standard deviations ranging from 1.5 % for the smallest volumes to less than 0.5 % for larger volumes, even with very viscous polymer solutions. We can also accurately pipette small cell suspension volumes, reproducibly transferring 5 x 105 cells in a volume of 13 µl with a standard deviation of less than 3 %. The automated process has been applied to the separation of differentiated and undifferentiated cells from the HL-60 cell line, achieving gentle, cost-effective and scalable purification of cell products without significantly influencing the cell viability.” To find out more about Tecan’s cell biology solutions, visit www.tecan.com/cellbiology For more information please contact Tecan Trading AG Antonietta Allocca Seestrasse 103 CH-8708 Männedorf Tel +41 (0)44 922 81 11 Fax +41 (0)44 922 81 12 info@tecan.com www.tecan.com About Tecan Tecan (www.tecan.com) is a leading global provider of laboratory instruments and solutions in biopharmaceuticals, forensics and clinical diagnostics. The company specializes in the development, production and distribution of automated workflow solutions for laboratories in the life sciences sector. Its clients include pharmaceutical and biotechnology companies, university research departments, and forensic and diagnostic laboratories. As an original equipment manufacturer (OEM), Tecan is also a leader in developing and manufacturing OEM instruments and components that are then distributed by partner companies. Founded in Switzerland in 1980, the company has manufacturing, research and development sites in both Europe and North America and maintains a sales and service network in 52 countries. In 2014, Tecan generated sales of CHF 400 million (USD 437 million; EUR 331 million). Registered shares of Tecan Group are traded on the SIX Swiss Exchange (TECN; ISIN CH0012100191).

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Comprehensive reader control and data processing software Tecan’s universal data processing software, is available for our complete line of microplate readers. It offers powerful data analysis capabilities, excellent data presentation and outstanding graphical flexibility. Magellan is fully compatible with Tecan’s automated Freedom EVO® and Freedom EVOlyzer® liquid handling workstations. Full ELISA and EIA AnalysesPerforms full qualitative and quantitative EIA analysis.All major curve fittings are provided – point to point, linear regression, non-linear regression, polynomial, cubic spline, Akima, LogitLog, four- and five-parameter fit.Convenient handling of dilution series and ICx calculation.General data import and export options as well as automated import of sample ID lists.Show more Full Kinetic Data AnalysesKinetic data analysis with calculation of slopes, onsets and enzyme kinetics; calculation of Michaelis-Menten constant according to Lineweaver-Burk, Eadie-Hofstee and Hanes equations. Easy to learnA number of video-based tutorials are provided with the Magellan package for immediate access to the software’s broad capabilities.A number of video-based tutorials are provided with the Magellan package for immediate access to the software’s broad capabilities. A wizard-based user interface guides you through the software, step by step, putting you in complete control from the start.The software has a variety of example files available for different application-related data functions, such as dilution series, trans- formations and standard curves.Show more Key highlights of Magellan Ideal for many different microplate-based applications.Full qualitative and quantitative, ELISAs, endpoint assays analyses.Kinetic Assays.Ratiometric measurements.Multi-label measurements.Spectral scanning of unknown samples.All major curve fittings are provided – point to point, linear regression, non-linear regression, polynomial, cubic spline, Akima, LogitLog, four- and five-parameter fit.Convenient handling of dilution series and IC50, ICx calculation.Kinetic data analysis.Spectra calculation provides rapid background correction, curve smoothing, wavelength selection, peak identification and 3D scanning tools.Provides fast analysis capabilities – from data reduction and curve fitting to calculation of kinetic parameters, such as the Michaelis-Menten constant.Quality validated – complies with ISO 13485 requirements and meets industry standards for its use, data integrity and security.Plate definition editor allows an easy creation or optimization of customized micro plate geometry files.General data import and export options for LIS and LIMS solutions as well as automated import of sample ID lists.Programming interface for integration into 3rd party devices available on request.Optional extra – can be supplied as Standard or Tracker version for all Tecan readers.Data security – Magellan Tracker to support FDA 21 CFR Part 11 compliance. Provides audit trail, electronic signatures, electronic records and user administration.Getting started – learning tutorials, virtual classrooms, example files and nine different GUI languages are available.Convenient automation – adds full data analysis capacity to Tecan’s automated Freedom EVO and Fluent processing systems.Fully backwards compatible suitable for all Tecan microplate readers. Full ELISA and EIA Analyses Sophisticated Quality Control FeaturesMagellan also includes inner

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Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. “The best reader for analyzing drug candidates.” "The Spark instrument has been the best reader for analyzing our samples, candidates for new drugs. Tecan support has been very helpful in optimizing the software applications to our needs." Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. “A must have in the lab.” "Easy to use and to achieve high quality, reproducible results." Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. “It is handy to have in the lab.” “The plate reader is easy to use and straight forward. Support usually comes pretty quickly too.” Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. “Great for protein assays.” "I have used the Tecan Spark plate reader for over a year. It is a very robust, easy-to-use instrument. When it comes to protein aggregation kinetics, life becomes so much easier with this instrument. I don’t have to worry about reproducibility, and we can monitor continuously, even at physiological temperature." Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star Copy 4 #FECB01 Created with Sketch. Star. Tecan Freedom EVO Gen-Probe 100/4 DTS. used. Manufacturer: Tecan; Model: Freedom EVO; The Tecan Freedom EVO GEN-Probe 100 /4 DTS is a liquid handling instrument designed for

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Our expertise. Life SciencesAdvance research and accelerate clinical impact with our reagents, automation solutions and applications expertise. DiagnosticsScale clinical diagnostic solutions with our reagents, automation and deep regulatory expertise. PartneringExpedite your healthcare innovation and gain a competitive edge with our OEM services and solutions. set offline anta //--> Customer stories.​ Novel methods guiding cancer treatment The UK company, The Binding Site, partnered with Tecan to automate their innovative multiple myeloma diagnostic method, providing more accurate results and faster access for patients. Post-mortem RNA sequencing revolutionizes neurological research Tecan's Trio RNA-Seq kit aids Cerevance in studying neurodegenerative disorders, offering high sensitivity for enhanced disease understanding and drug discovery. State-of-the-art assays for myasthenia gravis Tecan offers a gold-standard test for Myasthenia Gravis, aiding in early diagnosis and treatment to improve patients' quality of life and health outcomes. Their highly specific biomarkers and targeted assays are instrumental in this effort. Latest innovations.​ Uno Single Cell Dispenser™Automate single cell dispensing in MS-based single-cell analysis, iPSC libraries, 3D cell research, cell-line development and beyond. Resolvex® PrepThe ideal solution for low-to-medium throughput sample preparation in chromatography and mass spectrometry laboratories. Phase Separator™Process more samples in less time without compromising on accuracy. Solution made for customers in liquid biopsy and biobanking. set offline anta //--> The latest Tecan News and Events News Events 18 Mar 2025 Tecan publishes agenda for the Annual General Meeting 2025 12 Mar 2025 Tecan reports 2024 financial results, enhancing operational resilience amid challenging conditions 05 Mar 2025 Tecan schedules conference call on March 12 to discuss Full-Year 2024 Financial Results 27 Jan 2025 Tecan introduces Veya: bringing digital, scalable automation to labs worldwide 08 Jan 2025 Tecan meets revised sales outlook for fiscal year 2024 Customer news Corporate news 25-27 Mar 2025 Forum Labo 2025, Paris, France 11-15 Apr 2025 Global Congress

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Substrates in aqueous buffers, and inhibitors or other small molecules in DMSO. Learn more qPCR Set-UpThe Tecan D300e’s PCR wizard makes it quick and easy to set up (q)PCR reactions in just 4 guided steps. Miniaturize your reaction volume and save on reagents and precious samples. Learn more Time SavingsThe Tecan D300e makes long, laborious workflows possible to standardize. This technology removes the need for many wasteful steps, getting to results faster. The Tecan D300e is a cost-effective solution designed to accelerate drug discovery workflows by:Reducing titration times from hours or days to minutesAllowing drug discovery biologists to quickly and easily perform their own titrationsProviding greater access to titration and IC50 data Show more Tecan Journal 02/2017 Working towards cancer-free childhoods Read more //--> Tecan Journal 02/2017 Taking the guesswork out of drug development Read more //--> The system’s powerful software combines advanced experimental design with intuitive operation, allowing you to set up a wide range of experiments – including synergistic studies and randomized plate layouts – in minutes, saving you time without compromising on quality.Expert training by Tecan ensures instant operation of the digital dispenser. D300e Control Software Tecan D300e can deliver any dose in any wellLearn more Plate randomization can be made with one clickLearn more Synergy Wizard allows users to create synergy experiments in minutesLearn more Set up your PCR reaction in just 4 simple stepsLearn more D300eControl Software for integration into 21 CFR Part 11 compliant workflows The D300eControl Quality Assurance software is a standalone software that does not only contain all the control functionalities of the original D300eControl but also brings a host of additional features designed to be integrated into 21 CFR Part 11 compliant workflows.Watch the webinar and read the flyer to learn. Webinar: The new D300eControl Quality Assurance SoftwareLearn more Flyer D300eControl

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Plate and plate-to-plate quality control tools to track and store quality values and calibration curve data.Based on the Westgard multirule, where control results are compared against the expected mean and standard deviation, you can easily judge the acceptability of an analytical result.Available for Sunrise™, Infinite® F50 and Infinite® 200 PRO readers.Show more Convenient handling of ICx calculation Choose the most appropriate package for your needs. Magellan StandardMagellan Standard – intended as reader control and data analysis software for research use in pharmaceutical, biotechnological and life science industries, for food analysis and veterinary applications. Magellan Standard supports all plate formats up to 1536-wells and allows endpoint and kinetic data analysis, analysis of multi-label assays and multiple plates as well as spectra calculation and 3D scans. Magellan TrackerMagellan Tracker – offers all functionality for compliance with the FDA regulation 21 CFR part 11 for electronic records and signatures in addition to the functionality of Magellan Standard. See here the comparison of our software. Easy to useMagellan is an easy-to-use wizard-based data analysis software. Practical wizards give step-by-step guidance through the software and help you to tailor your assay and calculation. The following wizards are available:Evaluate results wizardCreate and edit sample ID lists wizardCreate and edit methods (analysis protocols) wizardAll this in 9 languages! Magellan StandardMagellan Standard is the software version for research and offers powerful data reduction such as:Spectra data reduction3D-scanKinetic analysisWide selection of predefined plate formatsAll major curve fittingsICx calculation Magellan TrackerMagellan Tracker offers the functionality of the Standard version and fulfills the regulatory requirements of the FDA regulation 21 CFR part 11:User administrationAudit trailElectronic records and signatures Plate Geometry EditorMagellan offers a wide selection of predefined plate formats. In addition, the wizard-based Plate Geometry Editor allows you to easily create new plate files or edit existing ones according to your needs. Convenient AutomationIf you need to expand your system, you can still use Magellan to provide powerful data reduction. Magellan extends to the Connect™ Stacker system and adds full data analysis capacity to Tecan’s Fluent® Laboratory Automation Solution, Freedom EVO® and Freedom EVOlyzer® processing systems. Magellan SpecificationsSystem requirements Operating systemWindows® XP Professional, Windows Vista® 32 bit, Windows 7, Windows 8, Windows 10SpreadsheetExcel® 32-Bit (2000, XP, 2003, 2007, 2010, 2013, 2016)Screen Resolution1024 x 600 (recommended 1680 x 1050)USB port1 (recommended 2) USB 2.0 Compatibility to Microplate ReadersDepending on the version, Magellan supports the complete line of Tecan microplate readers including previous models and the stacking device Tecan Connect™.Sunrise™Infinite® F50Infinite® 200 / 200 PRO seriesInfinite® F500Infinite® M1000 Compatibility to Robotic SoftwareFluent®Freedom EVOware®Freedom EVOlution™FACTS™Gemini™ Software For details please refer to the Magellan instruction for use Magellan Tutorial Intro Method Workspace set offline anta //--> Getting Started Get Raw Data Plate Layout set offline

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Of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID Global), Vienna, Austria 30 Apr - 02 May 2025 DeviceTalks Boston 2025, Boston, MA, United States 04-06 May 2025 ALDA 2025 Spring Senior Executive Conference, Boston, MA, United States 20-22 May 2025 SLAS Europe 2025, Hamburg, Germany Show more News 18 Mar 2025 Tecan publishes agenda for the Annual General Meeting 2025 12 Mar 2025 Tecan reports 2024 financial results, enhancing operational resilience amid challenging conditions 05 Mar 2025 Tecan schedules conference call on March 12 to discuss Full-Year 2024 Financial Results 27 Jan 2025 Tecan introduces Veya: bringing digital, scalable automation to labs worldwide 08 Jan 2025 Tecan meets revised sales outlook for fiscal year 2024 Show more Events 25-27 Mar 2025 Forum Labo 2025, Paris, France 11-15 Apr 2025 Global Congress of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID Global), Vienna, Austria 30 Apr - 02 May 2025 DeviceTalks Boston 2025, Boston, MA, United States 04-06 May 2025 ALDA 2025 Spring Senior Executive Conference, Boston, MA, United States 20-22 May 2025 SLAS Europe 2025, Hamburg, Germany Show more. Tecan Freedom EVO Gen-Probe 100/4 DTS. used. Manufacturer: Tecan; Model: Freedom EVO; The Tecan Freedom EVO GEN-Probe 100 /4 DTS is a liquid handling instrument designed for Tecan Freedom EVO 200, Tecan, tecan robot, tecan freedom evo Customer Satisfaction is our number one goal All lab equipment in stock already tested and ships in 1-3 days

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Are you tired of manual pipetting?Serial dilutions can be a thing of the past! Dispense directly from your stock solution to any plate format (12-1536 well plates). Take advantage of our dedicated software wizards for dose-response, synergy, PCR or enzyme profile experiements.Finally - normalize and randomize the layout to improve reliability of collected data. Find out how Tecan D300e can save your day in the lab! The Tecan D300e Digital Dispenser offers a simple method for generating dose-response curves, synergy experiments, enzyme profiles and setting up PCR reactions.Using HP’s Direct Digital Dispensing technology, it provides picoliter to microliter non-contact dispensing of liquids directly into the assay plate, saving time, minimizing consumption of valuable samples and accelerating research. D300e highlights Flexible Plate MapsCreate any plate map and dispense any dose in any well. Even randomize the plate with only one click! The Tecan D300e's software is so simple to use that one can create any plate map desired in only minutes! Digital TitrationUse your time more efficiently in follow up studies. D300eControl software makes it easy to generate dilution series, leading to more precise determination of Hill slopes and IC50 values. Minimizes manual pipetting, enabling scientists to focus on more important tasks and reducing repetitive strain injuries. Enhances throughput with simple, yet sophisticated, software and application-focused wizards. Automatically calculates all concentrations and volumes for faster, simpler plate set-up.Dispense your reagents directly into your assay plate and onto your cells. Show more Drug Combination StudiesIn vitro drug combination studies are becoming more and more. The Tecan D300e, due to independent dosing of each compound and a software wizard, finally makes it possible to execute these experiments with ease. Learn more Enzyme ProfilesThe Tecan D300e’s Enzyme Profile wizard makes it quick and easy to set up titrations using differing combinations of enzymes or

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Sample throughput and the number of cell line panels handled, as well as enhancing workflow efficiency. AstraZeneca scientists engaged in surface plasmon resonance studies are reaping the benefits of a recently acquired HP D300 Digital Dispenser, saving time, enhancing consistency and using significantly less compound for dose-response experiments. Tecan has worked with promega to demonstrate the suitability of the Infinite® 200 PRO and HP D300 Digital Dispenser for real-time kinetic investigation of cytotoxicity using Promega’s CellTox™ Green Dye. GlaxoSmithKline’s quest for improved anti-malarial treatments has been revolutionized by the speed and reliability of the HP D300 Digital Dispenser. This innovative system has increased throughput for standard drug titrations and enabled combinations of candidate compounds to be tested much more easily. Symrise is using an HP D300 Digital Dispenser to improve throughput and reproducibility in its cell and molecular biology laboratories, offering more reproducible results for cosmetic active ingredient testing. The Stanford genome Technology Center has invested in an HP D300 Digital Dispenser to study the effects of small molecule chemical inhibitors in yeast, enabling more experiments to be carried out more easily, and in less time. TES Pharma is a specialist biotechnology company which performs molecular, cellular and ADME screening for drug discovery. The Company has recently purchased an HP D300 Digital Dispenser, and is now reaping the benefits of direct titration with improved assay reproducibility and more time to perform exploratory research. In the last issue of the Tecan Journal, we announced the availability of the revolutionary HP D300 Digital Dispenser exclusively through Tecan’s Life Science Business. As customers in Europe and North America begin to place their orders, Kevin Peters, HP Global Sales Development Manager, reports on early customer experiences with the new technology.. Tecan Freedom EVO Gen-Probe 100/4 DTS. used. Manufacturer: Tecan; Model: Freedom EVO; The Tecan Freedom EVO GEN-Probe 100 /4 DTS is a liquid handling instrument designed for

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Proper hydration throughout the procedure. After the ischemia period, the clamps were removed, and the incisions were sutured. Mice were injected with 0.05 ml/g body weight pre-warmed (37 ˚C) saline subcutaneously previously described [2, 4]. Then, the mice were placed in temperature-controlled cages for recovery. To manage pain, mice received Buprenorphine (3.5 µl/g body weight) between 8 and 12 h post-surgery. At 24 h post-IR, the mice were then euthanized by CO2 asphyxiations and kidney tissues harvested for gene and protein expression analysis. Nephrectomized kidneys collected at 0 h served as controls for each mouse.Kidney injury assessmentBlood samples were obtained by tail nicking at 0 h and by cardiac puncture at 24 h post-IR. The blood samples were processed as previously described [4] to obtain plasma, which were stored in aliquots at -80 ˚C until used to assess kidney injury. Plasma levels of neutrophil gelatinase-associated lipocalin (NGAL) were assayed to confirm kidney injury using Enzyme-linked immunosorbent assays (ELISA). Previous studies by our group and others have established that serum creatinine (SCr) is less sensitive as a biomarker of acute kidney injury (AKI) when compared to NGAL and Cystatin C, especially in the early phase [17,18,19,20,21,22,23,24]. The ELISA utilized commercial NGAL assay kits (R&D Systems, Minneapolis, MN) and followed the manufacturer’s instructions. A Tecan Infinite 200 PRO plate reader (Tecan, Untersbergstraße, Austria) was used to read absorbance at nm 540 and nm 450. GraphPad Prism 7.0 software was used for generating standard curves, extrapolating values for the ELISA assays, and for subsequent statistical analysis of the data.Processing kidney tissueThe excised kidneys were decapsulated and sectioned into three parts; (1) a 2 mm mid-section was processed for immunohistochemical analysis. This section was fixed in formaldehyde overnight at 4 ˚C then placed in 70% ethanol at 4 ˚C, before paraffin embedding, and sectioned onto slides. (2) a second section for protein extraction, was wrapped in aluminum foil, snap-frozen in liquid nitrogen, and stored at -80 ˚C. (3) a third section was processed for RNA extraction – this was placed in RNALater®(Invitrogen, Waltham, MA) at 4 ˚C overnight. The RNALater® was then aspirated and the tissues stored at -80 ˚C. `.RNA extraction and cDNA synthesisThe frozen kidney tissues were thawed on ice, homogenized using a tissue homogenizer (Bead Mill 4 Homogenizer, 2016 Thermo Fisher Scientific Inc). Total RNA was extracted using Qiagen’s RNeasy Mini Kit, according to the manufacturer’s protocol. Total RNA concentration and