Tecan evo

June 9, 2015 | Customer News June 9, 2015 Tecan’s Freedom EVO® ideal for automated high throughput cell separation Männedorf, Switzerland, June 9, 2015 – The Karlsruhe Institute of Technology has automated high throughput cell separation protocols using aqueous two-phase systems (ATPS) on a Freedom EVO® 200 liquid handling platform. PhD student Sarah Zimmermann explained: “ATPS offers many advantages compared to antibody-based methods of cell separation; cost-effectiveness, scalability and very mild, gentle conditions for purification of cell products. Initially, we performed ATPS manually, but this is tricky and can give rise to large errors and unreproducible data. Automation was the way forward.” “The Freedom EVO workstation has enabled us to establish automated high throughput screening, allowing rapid, directed design of purification protocols for therapeutic cells. The process is more rapid and reproducible than manual methods, enabling 96 samples to be processed in four hours. Volumes between 10 and 990 µl are pipetted using the Liquid Handling Arm with fixed tips, with standard deviations ranging from 1.5 % for the smallest volumes to less than 0.5 % for larger volumes, even with very viscous polymer solutions. We can also accurately pipette small cell suspension volumes, reproducibly transferring 5 x 105 cells in a volume of 13 µl with a standard deviation of less than 3 %. The automated process has been applied to the separation of differentiated and undifferentiated cells from the HL-60 cell line, achieving gentle, cost-effective and scalable purification of cell products without significantly influencing the cell viability.” To find out more about Tecan’s cell biology solutions, visit www.tecan.com/cellbiology For more information please contact Tecan Trading AG Antonietta Allocca Seestrasse 103 CH-8708 Männedorf Tel +41 (0)44 922 81 11 Fax +41 (0)44 922 81 12 info@tecan.com www.tecan.com About Tecan Tecan (www.tecan.com) is a leading global provider of laboratory instruments and solutions in biopharmaceuticals, forensics and clinical diagnostics. The company specializes in the development, production and distribution of automated workflow solutions for laboratories in the life sciences sector. Its clients include pharmaceutical and biotechnology companies, university research departments, and forensic and diagnostic laboratories. As an original equipment manufacturer (OEM), Tecan is also a leader in developing and manufacturing OEM instruments and components that are then distributed by partner companies. Founded in Switzerland in 1980, the company has manufacturing, research and development sites in both Europe and North America and maintains a sales and service network in 52 countries. In 2014, Tecan generated sales of CHF 400 million (USD 437 million; EUR 331 million). Registered shares of Tecan Group are traded on the SIX Swiss Exchange (TECN; ISIN CH0012100191).

Comprehensive reader control and data processing software Tecan’s universal data processing software, is available for our complete line of microplate readers. It offers powerful data analysis capabilities, excellent data presentation and outstanding graphical flexibility. Magellan is fully compatible with Tecan’s automated Freedom EVO® and Freedom EVOlyzer® liquid handling workstations. Full ELISA and EIA AnalysesPerforms full qualitative and quantitative EIA analysis.All major curve fittings are provided – point to point, linear regression, non-linear regression, polynomial, cubic spline, Akima, LogitLog, four- and five-parameter fit.Convenient handling of dilution series and ICx calculation.General data import and export options as well as automated import of sample ID lists.Show more Full Kinetic Data AnalysesKinetic data analysis with calculation of slopes, onsets and enzyme kinetics; calculation of Michaelis-Menten constant according to Lineweaver-Burk, Eadie-Hofstee and Hanes equations. Easy to learnA number of video-based tutorials are provided with the Magellan package for immediate access to the software’s broad capabilities.A number of video-based tutorials are provided with the Magellan package for immediate access to the software’s broad capabilities. A wizard-based user interface guides you through the software, step by step, putting you in complete control from the start.The software has a variety of example files available for different application-related data functions, such as dilution series, trans- formations and standard curves.Show more Key highlights of Magellan Ideal for many different microplate-based applications.Full qualitative and quantitative, ELISAs, endpoint assays analyses.Kinetic Assays.Ratiometric measurements.Multi-label measurements.Spectral scanning of unknown samples.All major curve fittings are provided – point to point, linear regression, non-linear regression, polynomial, cubic spline, Akima, LogitLog, four- and five-parameter fit.Convenient handling of dilution series and IC50, ICx calculation.Kinetic data analysis.Spectra calculation provides rapid background correction, curve smoothing, wavelength selection, peak identification and 3D scanning tools.Provides fast analysis capabilities – from data reduction and curve fitting to calculation of kinetic parameters, such as the Michaelis-Menten constant.Quality validated – complies with ISO 13485 requirements and meets industry standards for its use, data integrity and security.Plate definition editor allows an easy creation or optimization of customized micro plate geometry files.General data import and export options for LIS and LIMS solutions as well as automated import of sample ID lists.Programming interface for integration into 3rd party devices available on request.Optional extra – can be supplied as Standard or Tracker version for all Tecan readers.Data security – Magellan Tracker to support FDA 21 CFR Part 11 compliance. Provides audit trail, electronic signatures, electronic records and user administration.Getting started – learning tutorials, virtual classrooms, example files and nine different GUI languages are available.Convenient automation – adds full data analysis capacity to Tecan’s automated Freedom EVO and Fluent processing systems.Fully backwards compatible suitable for all Tecan microplate readers. Full ELISA and EIA Analyses Sophisticated Quality Control FeaturesMagellan also includes inner

Our expertise. Life SciencesAdvance research and accelerate clinical impact with our reagents, automation solutions and applications expertise. DiagnosticsScale clinical diagnostic solutions with our reagents, automation and deep regulatory expertise. PartneringExpedite your healthcare innovation and gain a competitive edge with our OEM services and solutions. set offline anta //--> Customer stories.​ Novel methods guiding cancer treatment The UK company, The Binding Site, partnered with Tecan to automate their innovative multiple myeloma diagnostic method, providing more accurate results and faster access for patients. Post-mortem RNA sequencing revolutionizes neurological research Tecan's Trio RNA-Seq kit aids Cerevance in studying neurodegenerative disorders, offering high sensitivity for enhanced disease understanding and drug discovery. State-of-the-art assays for myasthenia gravis Tecan offers a gold-standard test for Myasthenia Gravis, aiding in early diagnosis and treatment to improve patients' quality of life and health outcomes. Their highly specific biomarkers and targeted assays are instrumental in this effort. Latest innovations.​ Uno Single Cell Dispenser™Automate single cell dispensing in MS-based single-cell analysis, iPSC libraries, 3D cell research, cell-line development and beyond. Resolvex® PrepThe ideal solution for low-to-medium throughput sample preparation in chromatography and mass spectrometry laboratories. Phase Separator™Process more samples in less time without compromising on accuracy. Solution made for customers in liquid biopsy and biobanking. set offline anta //--> The latest Tecan News and Events News Events 18 Mar 2025 Tecan publishes agenda for the Annual General Meeting 2025 12 Mar 2025 Tecan reports 2024 financial results, enhancing operational resilience amid challenging conditions 05 Mar 2025 Tecan schedules conference call on March 12 to discuss Full-Year 2024 Financial Results 27 Jan 2025 Tecan introduces Veya: bringing digital, scalable automation to labs worldwide 08 Jan 2025 Tecan meets revised sales outlook for fiscal year 2024 Customer news Corporate news 25-27 Mar 2025 Forum Labo 2025, Paris, France 11-15 Apr 2025 Global Congress

Substrates in aqueous buffers, and inhibitors or other small molecules in DMSO. Learn more qPCR Set-UpThe Tecan D300e’s PCR wizard makes it quick and easy to set up (q)PCR reactions in just 4 guided steps. Miniaturize your reaction volume and save on reagents and precious samples. Learn more Time SavingsThe Tecan D300e makes long, laborious workflows possible to standardize. This technology removes the need for many wasteful steps, getting to results faster. The Tecan D300e is a cost-effective solution designed to accelerate drug discovery workflows by:Reducing titration times from hours or days to minutesAllowing drug discovery biologists to quickly and easily perform their own titrationsProviding greater access to titration and IC50 data Show more Tecan Journal 02/2017 Working towards cancer-free childhoods Read more //--> Tecan Journal 02/2017 Taking the guesswork out of drug development Read more //--> The system’s powerful software combines advanced experimental design with intuitive operation, allowing you to set up a wide range of experiments – including synergistic studies and randomized plate layouts – in minutes, saving you time without compromising on quality.Expert training by Tecan ensures instant operation of the digital dispenser. D300e Control Software Tecan D300e can deliver any dose in any wellLearn more Plate randomization can be made with one clickLearn more Synergy Wizard allows users to create synergy experiments in minutesLearn more Set up your PCR reaction in just 4 simple stepsLearn more D300eControl Software for integration into 21 CFR Part 11 compliant workflows The D300eControl Quality Assurance software is a standalone software that does not only contain all the control functionalities of the original D300eControl but also brings a host of additional features designed to be integrated into 21 CFR Part 11 compliant workflows.Watch the webinar and read the flyer to learn. Webinar: The new D300eControl Quality Assurance SoftwareLearn more Flyer D300eControl

Of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID Global), Vienna, Austria 30 Apr - 02 May 2025 DeviceTalks Boston 2025, Boston, MA, United States 04-06 May 2025 ALDA 2025 Spring Senior Executive Conference, Boston, MA, United States 20-22 May 2025 SLAS Europe 2025, Hamburg, Germany Show more News 18 Mar 2025 Tecan publishes agenda for the Annual General Meeting 2025 12 Mar 2025 Tecan reports 2024 financial results, enhancing operational resilience amid challenging conditions 05 Mar 2025 Tecan schedules conference call on March 12 to discuss Full-Year 2024 Financial Results 27 Jan 2025 Tecan introduces Veya: bringing digital, scalable automation to labs worldwide 08 Jan 2025 Tecan meets revised sales outlook for fiscal year 2024 Show more Events 25-27 Mar 2025 Forum Labo 2025, Paris, France 11-15 Apr 2025 Global Congress of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID Global), Vienna, Austria 30 Apr - 02 May 2025 DeviceTalks Boston 2025, Boston, MA, United States 04-06 May 2025 ALDA 2025 Spring Senior Executive Conference, Boston, MA, United States 20-22 May 2025 SLAS Europe 2025, Hamburg, Germany Show more